The work scopes a summary of the activities of the Biological Threats Identification and Countermeasure Center from its creation until now. The unique contribution of the Center for the Polish Armed Forces resulting from the synergy of research and development, advisory and expert activities as well as clinical and environmental diagnostics in the area of biological agents of weapons of mass destruction was underlined in particular. Over the 20 years, BTICC has accumulated high-class specialists with knowledge, skills, competence and experience, as well as unique research infrastructure which allowed not only to be an important player for the military health service or CBRN (chemical, biological, radiological, nuclear) defense system, but also to carry out important scientific projects or advisory works for domestic or foreign stakeholders.