Urticaria is a heterogeneous disease characterized by formation of itchy bumps as a primary exanthema. An important role in the pathomechanism plays secretion of inflammatory mediators such as histamine, leukotrienes and prostaglandins from mast cells in subepidermal layers. The etiology of lesions is various. The most common causes of acute urticaria are food allergies and medications, but it is often not possible to determine the causative agent for chronic urticaria (spontaneous urticaria). The paper presents a case of a 42‑year‑old female with recurrent urticaria, which was associated by the patient with consuming some kinds of food, especially spices, cold meat and canned food, which was associated with reactions to food additives. During a double‑blind, placebo‑controlled food challenge (DBPCFC), sodium benzoate and sodium glutamate intolerance has been shown in the patient.