Lymphomas are a diverse group of lymphoid neoplasms that can develop in various parts of the body. This paper discusses four clinical cases of patients with lymphomas of the brain, orbit, mesentery and bone, with special emphasis on their morphology on magnetic resonance imaging, emphasizing the importance of this technique in diagnosis and assessment of disease progression. In each case, despite the different histological types, the characteristic imaging features of lymphomas, i.e. signal homogeneity in T1-weighted images, absence of cystic elements, intense contrast enhancement and diffusion restriction, were identified before treatment. Attention is given to the therapeutic implications of early suspicion of lymphoma and the importance of biopsy in confirming the diagnosis. The paper emphasizes that skillful interpretation of MRI images in the context of the overall clinical picture can significantly shorten the diagnostic process and accelerate the implementation of targeted treatment in the affected patients.