The study presents a current state of knowledge following a year of our experience with a COVID‑19 pandemic, especially regarding the issues that arose while caring for asthma and allergy patients. It generally shows a cellular mechanism of SARS‑CoV‑2 infection, its clinical presentation and consequences. A risk and course of infection in asthma and allergy patients, as well as the COVID‑19 potential impact on asthma flare‑ups were discussed. The paper describes how to treat asthma flare‑ups during the COVID‑19 pandemic, how to proceed with asthma flare‑up patients infected with COVID‑19, how to treat chronic asthma during the COVID‑19 pandemic and which medical and diagnostic procedures should be limited. It presents the guidelines for allergists during the pandemic and for individual protection of health professionals delivering asthma and allergy care in the era of the pandemic.