Levetiracetam – known and possible applications
More details
Hide details
Uniwersytet Medyczny w Lublinie (absolwent, lekarz), Polska
Uniwersytet Medyczny w Lublinie (student), Polska
Submission date: 2022-12-20
Final revision date: 2023-01-21
Acceptance date: 2023-01-23
Publication date: 2023-06-30
Corresponding author
Klaudia Walczak   

Lekarz, Absolwent Uniwersytetu Medycznego w Lublinie, Polska
LW 2023;101(2):81–86
Introduction: The use of levetiracetam in treatment of epileptic seizures is well established in the literature. The article reviews uses of the drug in treatment of neurological disorders and potential research directions for it. Material and methods: The literature available in the PubMed database was reviewed using the following keywords: “levetiracetam”; “epilepsy”; “status epilepticus”; “Alzheimer’s disease”; “migraine”; “neuropathic pain”. Results: Levetiracetam is an antiepileptic drug. It has been approved by the FDA (Food and Drug Administration) for adjuvant treatment of focal, myoclonic and tonic-clonic seizures. The literature indicates that it is also effective for off-label uses – treatment of migraine, a mania episode in the course of bipolar affective disorder. Single studies imply its efficacy in treatment of Alzheimer’s disease. The most common adverse effects occurring during treatment with the drug are mild and resolve quickly. They include, among others: drowsiness, dizziness, irritability, anxiety or nasopharyngitis. Levetiracetam can be used for both paediatric population and adults. Conclusion: The use of levetiracetam represents an interesting direction in treatment of many neurological disorders. Drug uses described in the literature require additional research on a larger group of patients.