RESEARCH PAPER
Assessment of the relationship between sensitization to specific allergens and the presence of micturition disorders in children
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Wojskowy Instytut Medyczny - Państwowy Instytut Badawczy, Klinika Pediatrii, Nefrologii i Alergologii Dziecięcej, Polska
2
Wojskowy Instytut Medyczny - Państwowy Instytut Badawczy, Zakład Patomorfologii, Polska
Submission date: 2023-03-19
Final revision date: 2023-05-16
Acceptance date: 2023-06-20
Publication date: 2023-09-30
Corresponding author
Magda Paula Rakowska-Silska
Wojskowy Instytut Medyczny – Państwowy Instytut Badawczy, Klinika Pediatrii, Nefrologii i Alergologii Dziecięcej, Polska
LW 2023;101(3):226-233
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ABSTRACT
The relationship between exposure to allergens and presense of voiding disorders in the pediatric population has been observed for many years. The first such observation was documented in the 1930s. It was found that eliminatinon of allergen from the patient’s environment reduces not only allergic symptoms in the upper respiratory tract, but also reduces lower urinary tract sympoms.
The study included 40 children with confirmed sensitization in the IgE-mediated mechanism. Subsequently, patients were divided into 2 groups: with and without voiding disorders. Total IgE, specific IgE in inhalation and food panels were measured in all patients. Skin prick tests were performed. There was no statistically significant correlation between the total IgE concentration in groups of patients with allergy and micturition disorders and with allergy without micturition disorders. There were no differences in the number of allergens for which the increased concentration of specific IgE was obtained between the groups, both in the inhalant panel (p = 0.5) and the food panel (p = 0.45), the same result was obtained in skin prick tests. No significant differences were noted in the number of patients with the positive result of specific IgE for particular allergens between the groups. A severe sensitization (in class ≥ 3 or class ≥ 5) to any allergen has not been found to predispose children to micturition disorders. Summarizing the results, there was no relationship between micturition disorders and allergy to individual allergens. Based on the above data, it was found that the degree of polysensitization does not affect the occurrence of micturition
disorders in children.