REVIEW PAPER
Ocular manifestations of acromegaly
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Klinika Okulistyki CSK MON WIM w Warszawie; kierownik: płk prof. dr hab. n. med. Marek Rękas
Submission date: 2021-01-16
Publication date: 2017-10-02
LW 2017;95(4):401-405
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ABSTRACT
Acromegaly is a chronic disease caused by hypersecretion of growth hormone, in the course of which characteristic changes in appearance, metabolic disorders and the development of systemic complications occur. Acromegaly is characterized by various ocular symptoms. The most commonly observed vision disorder is bitemporal hemianopsia, as a result of compression of the optic chiasm by pituitary adenoma. In the course of acromegaly there are also changes in ocular structures and physiology unrelated to the tumor mass. Ocular symptoms of acromegaly include: increased central corneal thickness (CCT), increased intraocular pressure (IOP), change of biomechanical properties of the cornea, higher central retinal thickness, mild retinal edema, papilledema, diabetic retinopathy, enlarged extraocular muscles, exophthalmos, blepharoptosis, lacrimal gland enlargement, epiphora, pigmentary degeneration of the retina and choroidal melanoma. Patients with acromegaly should be under systematic and perceptive ophthalmological care.