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RESEARCH PAPER
Comparison of usefullness of FSE and SPGR sequences in diagnosis of ACTH‑secreting pituitary microadenomas
 
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1
Zakład Radiologii Lekarskiej CSK MON WIM w Warszawie; kierownik: dr n. med. Artur Maliborski
 
2
Radiologia, Szpital Medicover w Warszawie; kierownik: dr n. med. Rafał Kidziński
 
3
Klinika Neurochirurgii CSK MON WIM w Warszawie; kierownik: dr hab. n. med. Andrzej Koziarski
 
 
Submission date: 2018-12-04
 
 
Publication date: 2019-01-29
 
 
LW 2019;97(2):108-112
 
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ABSTRACT
Background. The aim of the study was an assessment of efficacy of MR T1‑weighted FSE and SPGR images in the diagnostic evaluation of ACTH‑secreting pituitary microadenomas. Methods. The study involved 15 patients with Cushing’s disease that underwent transsphenoidal surgery for pituitary tumor, whose histopathological examination confirmed ACTH‑secreting adenoma. Preoperative MR study was performed using 3T scanner with intravenous administration of contrast material. The findings of FSE and SPGR imaging were verified based on surgical localization of tumors. Results. The sensitivity of FSE and SPGR sequences for the correct localization of the adenomas was 60.0% (9 of 15) and 73.3% (11 of 15), respectively. Positive predictive value was 90% for FSE and 92% for SPGR. Mean tumor size was 3.5 mm +0.9 mm in MR studies and 2.7 mm +0.8 mm intraoperatively. Conclusions. Postcontrast T1‑weighted SPGR images are superior to FSE in the evaluation of pituitary ACTH‑secreting adenomas. It should be considered to include SPGR in the standard pituitary MR imaging protocol for patients with hypercortisolemia.
CONFLICT OF INTEREST
No conflicts of interest were declared.
eISSN:1509-5754
ISSN:0024-0745
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